About Dr. Martinez
Associate Professor
Ph.D., 1993, University of Wisconsin-Madison
Office Phone: 713-743-2662
Office: Engineering Building 2; Room: W208-D3 (2nd Floor)
Director, Connective Tissue Physiology Laboratory
Located within: Biomedical Engineering Research Core Laboratory
Lab Home Page: http://ctpl.uh.edu
Email: ddam@uh.edu
Scientific Expertise
Fig. 1a and 1b. AAV-GFP transfected into rat primary knee MCL fibroblasts. In Fig. 1a, DAPI stains the nucleus blue, and AAV-2-GFP is expressed as green fluorescent protein , 20x mag. In Fig. 1b, Alexa Fluor 555 Phalloidin stains intracellular actin orange, DAPI stains the nucleus blue and AAV-5-GFP is expressed as green fluorescent protein, 60x mag. Wound Healing
The biochemical characterization and molecular gene expression of extracellular matrix collagens; The regulation of collagen post-translational modifications; Growth factor and hormonal modification of the ECM in mineralized and non-mineralized connective tissues.
Gene Therapy Delivery into Connective Tissues
Adeno-associate virus and serotype specificity in primary and immortalized fibroblasts; Ex vivo delivery of viral vectors and localization; Cell signaling in engineered tissues.
Fig. 1a and 1b. AAV-GFP transfected into rat primary knee MCL fibroblasts. In Fig. 1a, DAPI stains the nucleus blue, and AAV-2-GFP is expressed as green fluorescent protein , 20x mag. In Fig. 1b, Alexa Fluor 555 Phalloidin stains intracellular actin orange, DAPI stains the nucleus blue and AAV-5-GFP is expressed as green fluorescent protein, 60x mag.