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Fortunately, in our generation, we have witnessed an explosive expansion in the knowledge of genomic sequences and thus born of genomics, proteomics, glycomics, and many other large scale biology fields. The following figure (Figure 1) provides a glimpse of the overall picture.

Figure 1. An account of the rich, accessible genetic information.

Large scale biology refers to systems with multiple components of biomolecules and/or biomolecular machines. Required by the studies of such complex systems, biological research has been increasingly conducted using the formats of miniaturized multiplex experiments (i.e., many experiments are combined into one or a few experiments and performed in parallel). The complexity of new experiments has been increasing as we examine the interactions of biomolecules, the signaling pathways of cellular activities, and the networking of cellular events, and as we attempt to reconstitute or create biomolecular machines.


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