2022 | |
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30 | P.-S. Huang†, Y.-H. Chen†, M.-H. Wen, and T.-Y. Chen* "Generation of a Homozygous Knock-In Human Embryonic Stem Cell Line Expressing mEos4b-Tagged CTR1" In preparation |
29 | Y. Zhang, P. Huang, and T.-Y. Chen* "Cu-dependent Intracellular Redox Response" In preparation |
28 | G. Yan, W. Shih, and T.-Y. Chen* "Inter-disc trapping boosts photo-enhanced catalysis of nano-plasmonic array" In preparation |
27 | M. Pan†, G. Yan†, A. G. Santiago,A. Keller, M. Lofgren, R. Banerjee, P. Chen*, and T.-Y. Chen* "Negative Cooperative Binding of AdoCbl for the Catalytic and Transfer Functions of ATR" In preparation |
26 | M.-H. Wen†, H. Chen†, G. Yan†,Y. Zhang, and T.-Y. Chen* "Cu Induces CTR1 Endocytosis through Modulating CTR1 Oligomer States" In preparation |
2021 | |
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25 | M.-H. Wen†, X. Xie†, P.-S. Huang, K. Yang, and T.-Y. Chen* "Crossroads between membrane trafficking machinery and copper homeostasis in the nerve system" Open Biology2021, 11, 210128. [pdf] |
24 | P.-S. Huang, M.-H. Wen, X. Xie, A. Xu, D.-F. Leeb, T.-Y. Chen* "Generation of a homozygous knock-in human embryonic stem cell line expressing SNAP-tagged SOD1" Stem Cell Res., 2021, 54, 102415. [pdf] |
2020 | |
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23 | H. Chen†, X. Xie†, T.-Y. Chen* "Single-Molecule Microscopy for In-Cell Quantification of Protein Oligomeric Stoichiometry" Curr. Opin. Struct. Biol., 2020, 66, 112-118. †: Co-first authors. [pdf] |
22 | M. Pan, Y. Zhang, G. Yan, T.-Y. Chen* "Dissection of interaction kinetics through single-molecule interaction simulation”. Analytical Chemistry" Anal. Chem., 2020, 92, 11582-11589. [pdf][SI] |
2019 | |
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21 | M.-H. Wen, X. Xie, J. Tu, D.-F. Lee, T.-Y. Chen* "Generation of a genetically modified human embryonic stem cell expressing fluorescence tagged ATOX1" Stem Cell Res., 2019, 41, 101631. [pdf] |
2018 | |
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20 | X. Xie†, Y.-S. Cheng†, M.-H. Wen, A. Calindi, K. Yang, C.-W. Chiu, T.-Y. Chen* "Quantifying the Oligomeric States of Membrane Proteins in Cells through Super-resolution Localizations" J. Phys.Chem. B 2018, 122(46), 10496-10504. †: Co-first authors. [pdf][SI] |
19 | T.-Y. Chen*, Y.-S. Cheng, P.-S. Huang, P. Chen* "Facilitated unbinding via multivalency-enabled ternary complexes: New paradigm for protein-DNA interactions" Acc. Chem. Res., 2018, 51, 860-868. [pdf] |
2017 | |
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18 | A. G. Santiago†, T.-Y. Chen†, L. A. Genova, W. Jung, A. M. G. Thompason, M. M. McEvoy, P. Chen.
“Adaptor Protein Mediates Dynamic Pump Assembly for Bacterial Metal Efflux”. Proc. Natl. Acad. Sci. U.S.A., 2017, 114, 6694-6699. †: Co-first authors. [pdf][SI] |
2016 | |
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17 | F. Yang, T.-Y. Chen, Ł. Krzemiński, A. G. Santiago, W. Jung, P. Chen.
“Single-Molecule Dynamics of the Molecular Chaperone Trigger Factor in Living Cells”. Mol. Microbiol., 2016, 102, 992-1003. [pdf][SI] |
16 | J. B. Sambur, T.-Y. Chen, E. Choudhary, G. Chen, E. J. Nissen, E. M. Thomas, N. Zou, P. Chen.
“Sub-particle reaction and photocurrent mapping to optimize catalyst-modified photoanodes”. Nature, 2016, 530, 77-80. [pdf][SI] |
2015 | |
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15 | T.-Y. Chen†, W. Jung†, A. G. Santiago, F. Yang, Ł. Krzemiński, P. Chen.
“Quantifying Multi-State Cytoplasmic Molecular Diffusion in Living Cells via Inverse Transform of Confined Displacement Distribution”. J. Phys. Chem. B, 2015 , 119, 14451-14459. †: Co-first authors. [pdf][SI] |
14 | D. J. Martell, C. P. Joshi, A. Gaballa, A. G. Santiago, T-Y. Chen, W. Jung, J. D. Helmann, P. Chen.
“Metalloregulator CueR biases RNA polymerase’s kinetic sampling of dead-end or open complex to repress or activate transcription”. Proc. Natl. Acad. Sci. U.S.A., 2015, 112, 13467-13472. [pdf] [SI] |
13 | T.-Y. Chen†, A. G. Santiago†, W. Jung, Ł. Krzemiński, F. Yang, D. J. Martell, J. D. Helmann, P. Chen.
“Concentration- and Chromosome-Organization-dependent Regulator Unbinding from DNA for Transcription Regulation in Living Cells”. Nat. Commun., 2015, 6, 7445. DOI: 10.1038/ncomms8445. †: Co-first authors. [pdf] [SI] News highlight: • "How Transcription Factors Depart Their Targets In Cells," Chemical & Engineering News, 2015, 93, 25. • "Research finds protein regulation linked to cells' growth cycle", Cornell Chronicle, July 2015. |
2013 | |
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12 | P. Chen, A. M. Keller, C. P. Joshi, D. J. Martell, N. M. Andoy, J. J. Benítez, T.-Y. Chen, A. G. Santiago, F. Yang.
Single-Molecule Dynamics and Mechanisms of Metalloregulators and Metallochaperones. Biochemistry, 2013, 52, 7170-7183. [pdf] |
11 | S. Maiti, H.-Y. Chen, T.-Y. Chen, C. -H. Hsia, D. H. Son. Effect of Surfactant and Solvent on Spin-Lattice Relaxation Dynamics of Magnetic Nanocrystals. J. Phys. Chem. B, 2013, 117 (16), 4399-4405. [pdf] |
2012 | |
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10 | C. P. Joshi, D. Panda, D. J. Martell, N. M. Andoy, T. -Y. Chen, A. Gaballa, J. D. Helmann, P. Chen.
Direct substitution and assisted dissociation pathways for turning off transcription by a MerR-family metalloregulator. Proc. Natl. Acad. Sci. U.S.A., 2012, 109, 15121-15126. [pdf] [SI] |
9 | M. Keller, J. Benitez, D. Klarin, L. Zhong, M. Goldfogel, F. Yang, T.-Y. Chen, P. Chen. Dynamic Multi-Body Protein Interactions Suggest Versatile Pathways for Copper Trafficking. J. Am. Chem. Soc., 2012, 134 (21), 8934-8943. [pdf] [SI] |
2011 | |
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8 | H.-Y. Chen, T.-Y. Chen, E. Berdugo, Y. Park, K. Lovering, D. H. Son.
Hot Electron from Consecutive Exciton-Mn Energy Transfer in Mn-Doped Semiconductor Nanocrystals. J. Phys. Chem. C, 2011, 115, 11407-11412. [pdf] |
2010 | |
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7 | T.-Y. Chen, C.-H. Hsia, H.-Y. Chen, D. H. Son.
Dynamics of Spin-Lattice Relaxation in CoxFe3-xO4 Nanocrystals. Ultrafast Phenomena XVII, 2010, 152-153. |
6 | T.-Y. Chen, C.-H. Hsia, H.-Y. Chen, D. H. Son.
Size Effect on Chemical Tuning of Spin-Lattice Relaxation Dynamics in Superparamagnetic Nanocrystals. J. Phys. Chem. C, 2010, 114, 9713-9719. [pdf] |
5 | H.-Y. Chen, T.-Y. Chen, D. H. Son.
Measurement of Energy Transfer Time in Colloidal Mn-Doped Semiconductor Nanocrystals. J. Phys. Chem. C, 2010, 114, 4418-4423. [pdf] |
2009 | |
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4 | C.-H. Hsia, T.-Y. Chen, D. H. Son.
Time-Resolved Study on Surface Spin Effect on Spin-lattice Relaxation in Fe3O4 nanocrystals;. J. Am. Chem. Soc., 2009, 131, 9146-9147. [pdf] |
2008 | |
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3 | T.-Y. Chen, C.-H. Hsia, D. H. Son.
Time-Dependent Elastic Properties and Lattice Temperature of the Photoexcited Iron Oxide Nanocrystals;. J. Phys. Chem. C, 2008, 112, 10125-10129. [pdf] |
2 | C.-H. Hsia, T.-Y. Chen, D. H. Son.
Size-Dependent Ultrafast Magnetization Dynamic in Iron Oxide Nanocrystals. Nano Lett., 2008, 8 (2), 571-576. [pdf] |
2007 | |
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1 | T.-Y. Chen, C.-H. Hsia, H. S. Son, D. H. Son.
Ultrafast Energy Transfer and Strong Dynamic non-Condon Effect on Ligand Field Transitions by Coherent Phonon in g -Fe2O3 Nanocrystals. J. Am. Chem. Soc., 2007, 129, 10829-10836. [pdf] |